Enzymes → affected by acidity or alkalinity of solutions in which they act
Some work best in acidic conditions (proteases in stomach) Some work best in alkaline conditions (intestinal enzymes)
When enzymes placed in pH conditions that vary from optimum, they start to denature
(extreme change in acidity or alkalinity of solutions denature the enzymes)
M: maximum activity of amylase of about 7 (Optimum pH)
As solution becomes acidic, (pH 7-5) or alkaline (pH 7-9), activity decreases
at pH4 or above pH 9 → enzyme is completely denatured
*Explanation is the same as the temperature section