Substance + explaination
1. Carbon Dioxide
→ product of aerobic respiration
→ carbon dioxide level in our blood is usually not harmful
→ in certain cases where there is abnormally high level of in our blood → a condition called hypercarbia occurs.
→ person may suffer from headache, confusion, rapid breathing and premature heartbeats.
⇒ excretory organ is the lungs. and it is excreted as gas in expired air.
2. Urea
digestive system breaks down proteins into amino acids. Absorbed amino acids ⇒ transported to liver, distributed around the body and then assimilated.
Liver → is involved in assimilation of amino acids.
→ uses amino acids to synthesise proteins found in blood plasma
these plasma proteins ⇒ include fibrinogen, which is essential for clotting of blood. Human Transport System Main Note

if we consume more proteins than we need → we will have excess amino acids in the blood
→ excess amino acids → are transported to the liver where they are deaminated through a process called deamination.
During deamination → part of the amino acid molecule is removed and converted to urea.
→ urea is then removed by kidneys

Is urea in blood harmful?
Urea → is a waste product formed in the breakdown of proteins
Nomral concentration of urea in blood is nor harmful
⇒ abnormally high urea concentration in blood → may cause abdominal pain, nausea, or vomiting
→ rare cases → can result in irregular heartbeat and muscle cramps
3. Mineral salts or ions
Bodies → need mineral salts
Deficiency of certain ions → may result in deficiency diseases.
Example: lack of calcium results in weakening of bones or osteoporosis

Excess salts or ions in blood → can be harmful.
⇒ may lower WP in blood plasma
Water may pass out of tissue cells into blood by osmosis.
Cells may become dehydrated (crenated) = Movement of Substances Main Note
⇒ Kidneys help to remove excess salts from the body
4. Water
Water → essential to life
⇒ produced during aerobic respiration
hence it is also a metabolic product

However → excess water in body is harmful
→ will increase WP in blood plasma
By Osmosis→ Water will enter tissue cells → cells may swell and burst
Hence excess water also has to be removed.